Iwatsubo K, Brav C, Uechi M, Baljinnyam E, Nakamura T, Umemura M, Lai L, Gao S, Yan L, Zhao X, Park M, Qiu H, Okumura S, Iwatsubo M, Vatner DE, Vatner SF, Ishikawa Y : Prevention of heart failure in mice by an antiviral agent that inhibits type 5 cardiac adenylyl cyclase

Am J Physiol Heart Circ Physiol 302, H2622-H2628, 2012 .


Yokoyama U, Ishiwata R, Jin MH, Kato Y, Suzuki O, Jin H, Ichikawa Y, Kumagaya S, Katayama Y, Fujita T, Okumura S, Sato M, Sugimoto Y, Aoki H, Suzuki S, Masuda M, Minamisawa S, Ishikawa Y : Inhibition of EP4 signaling attenuate aortic aneurysm formation.

PLoS One 7, e36724, 2012.


Ichikawa Y, Yokoyama U, Iwamoto M, Oshikawa J, Okumura S, Sato M, Yokota S, Masuda M, Asou T, Ishikawa Y : Inhibition of phosphodiesterase type 3 dilates the rat ductus arteriosus without inducing intimal thickening.

Circ J 76, 2456-2464, 2012.


Fukumura H, Sato M, Kezuka K, Sato I, Feng X, Okumura S, Fujita T, Yokoyama U, Eguchi H, Ishikawa Y, Saito T : Effects of ascorbic acid on reactive oxygen species production in chemotherapy and hyperthermia inprostate cancer cell.

J Physiol Sci 62, 251-257, 2012.


Kurotani R, Okumura S, Matsubara T, Yokoyama U, Buckley JR, Tomita T, Kezuka K, Nagano T, Esposito D, Taylor TE, Gillette WK, Ishikawa Y, Abe H, Ward JM, Kimura S : Secretoglobin 3A2 supresses bleomycin-induced pulmonary fibrosis by transforming growth factor b signaling down-regulation.

J Biol Chem 286, 19682-19692, 2011.


Yamagishi K, Onuma K, Chiba Y, Yagi S, Aoki S, Sato T, Sugawara Y, Hosoya N, Saeki Y, Takahashi M, Fuji M, Ohsaka T, Okajima T, Akita K, Suzuki T, Sunawongse P, Urushiyama A, Kawai K, Shoun H, Ishii Y, Ishikawa H, Sugiyama S, Nakajima M, Tsuboi M, Yamanaka T : Generation of gaseous sulfer-containing compounds in tumor tissue and suppression of gas diffusion as an antitumor treatment.

Gut 61, 554-561, 2011.


Sato M, Yokoyama U, Fujita T, Okumura S, Ishikawa Y : The role of cytochrome p450 in ischemic heart disease.

Curr Drug Metab 12, 526-532, 2011.


 Sato M, Hiraoka M, Suzuki H, Bai Y, Kurotani R, Yokoyama U, Okumura S, Cismowski MJ, Lanier SM, Ishikawa Y: Identification of transforming factor 3E3 (TFE3) as a receptor-independent activator of Ga16 

J Biol Chem 286, 17766-17776, 2011.


Suzuki S, Yokoyama U , Abe T, Kiyonari H, Yamashita N, Kato Y, Kurotani R, Sato M, Okumura S, Ishikawa Y: Differential roles of Epac in regulating cell death in neuronal and myocardial cells.

J Biol Chem, 285, 24248-24259, 2010.


Yokoyama U, Minamisawa S , Katayama A, Tang T, Suzuki S, Iwatsubo K, Iwasaki S, Kurotani R, Okumura S, Sato M, Yokota S, Hammond HK, Ishikawa Y : Differential regulation of vascular tone and remodeling via stimulation of type 2 and type 6 adenylyl cyclases in the ductus arteriosus.

Circ Res ,106, 1882-1892, 2010.


Otsu K, Toya Y, Oshikawa J, Kurotani R, Yazawa T, Sato M, Yokoyama U, Umemura S, Minamisawa S, Okumura S, Ishikawa Y : Caveolin gene transfer improves glucose metabolism in diabetic mice

Am J Physiol Cell Physiol ,298, C442-C445, 2010.